Subsequent breast cancer

Disease1 paper2 findings

Humans1

Associations

2

Pathogenic variants in breast cancer susceptibility genes

upin humans1

1 study

pathogenic variants in breast cancer susceptibility genes raise the risk of subsequent breast cancer in humans (7.4-fold greater risk (95% CI = 3.16 to 17.19)).
Humansin female childhood cancer survivors with WGSfemalesn = 3,292
Integrating genetic predictors into subsequent breast cancer risk prediction in survivors of childhood cancer · Journal of the National Cancer Institute · 9 Sep 2026

Polygenic risk score

upin humans1

1 study

Polygenic risk score raises the risk of subsequent breast cancer in humans (HR per SD = 1.71, 95% CI = 1.43 to 2.05).
Humansin female childhood cancer survivorsfemalesn = 5,388
Integrating genetic predictors into subsequent breast cancer risk prediction in survivors of childhood cancer · Journal of the National Cancer Institute · 9 Sep 2026

Polygenic risk score →

Latest

4

SurgeryHumans26 Sep

Evaluation of exogenous estrogen use in patients with lobular neoplasia and its role in subsequent breast cancer development

Obstetrics and GynecologyReview15 Sep

Rethinking Menopausal Hormone Therapy After Risk-Reducing Salpingo-Oophorectomy in Women at High Risk for Breast Cancer

Journal of the National Cancer InstituteHuman trial11 Sep

SHBG as a breast cancer risk biomarker in premenopausal women? Results from an individual patient's pooled analysis and a meta-analysis

Journal of the National Cancer InstituteHumans9 Sep

Integrating genetic predictors into subsequent breast cancer risk prediction in survivors of childhood cancer

ENDO 2025 AbstractHumans23 Oct

SAT-118 Untargeted Profiling of the Second Trimester Pregnancy Exposome Reveals an External Toxin Linked to Third Trimester Endocrine Disruption and Maternal Breast Cancer