Severe liver disease

1. GDF-15 raises the risk of severe liver disease in humans.

   HumansMendelian randomization analysis

   Large-Scale Plasma Proteomics Reveals Preclinical Biomarkers of Incident Severe Liver Disease · Proteomics. Clinical applications · 1 Sep 2026

2. GDF-15 predicts severe liver disease in humans (C-index 0.80).

   Humanscommunity-based cohort without baseline liver disease14.1 yearsn = 46,951

   Large-Scale Plasma Proteomics Reveals Preclinical Biomarkers of Incident Severe Liver Disease · Proteomics. Clinical applications · 1 Sep 2026

GDF-15 →