Serious bacterial infection

Disease1 paper2 findings

  • Humans1

Associations

2

SRSF2

upin humans1

1 study
  1. SRSF2 is associated with serious bacterial infection in humans (22–25% developed serious bacterial infection within 10 years).

    HumansExpanded SRSF2 P95 clones10 years

    Blood stem-cell mutations linked to serious bacterial infections · Nature communications · 7 Oct 2026

SRSF2 →

Clonal hematopoiesis of indeterminate potential

upin humans1HR 1.22

1 study
  1. Clonal hematopoiesis of indeterminate potential is associated with serious bacterial infection in humans (HR 1.22).

    HumansIndependent of malignancy and robust to adjustment for inflammatory comorbidities and ancestry

    Blood stem-cell mutations linked to serious bacterial infections · Nature communications · 7 Oct 2026

Clonal hematopoiesis of indeterminate potential →

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Nature CommunicationsHumans

Blood stem-cell mutations linked to serious bacterial infections

In an analysis of 889,215 people, clonal blood mutations were associated with serious bacterial infections, with a hazard ratio of 1.22.In an analysis of 889,215 people, clonal blood mutations were associated with serious bacterial infections, with a hazard ratio of 1.22.