Nociplastic pain

Disease

1 paper2 findings

  • Humans1

Effects

2

Psychological function

downin humans1

1 study
  1. Nociplastic pain impairs psychological function in humans (β = -0.639 (-0.93, -0.35), p < 0.0001).

    “psychological functioning (β=-0.639 (-0.93, -0.35), p < 0.0001) after adjusting for demographics, comorbidities, pain intensity, and opioid use.”

    Humansin aging veterans with chronic low back pain

    Nociplastic Features Associate with Poorer Function in Aging Veterans with Chronic Low Back Pain

    GSA 2025 abstract31 Dec 2025

Physical function

downin humans1

1 study
  1. Nociplastic pain impairs physical function in humans (β = -0.30 (-0.49, -0.12), p < 0.0001).

    “More severe nociplastic features were significantly associated with poorer physical (β =-0.30 (-0.49, -0.12), p < 0.0001) and psychological functioning”

    Humansin aging veterans with chronic low back pain

    Nociplastic Features Associate with Poorer Function in Aging Veterans with Chronic Low Back Pain

    GSA 2025 abstract31 Dec 2025

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