Neovascular AMD

Disease1 paper2 findings

  • Humans1

Associations

2

Antihypertensive medication class count

upin humans1HR 1.3

1 study
  1. antihypertensive medication class count raises the risk of neovascular AMD in humans (HR 1.30, 95% CI 1.05–1.62).

    Humansunivariate analysis, per additional medication class

    Chronic Hypertension and Conversion from Intermediate Age-Related Macular Degeneration (iAMD) to the Advanced Phenotypes · Ophthalmic epidemiology · 25 Aug 2026

Hypertension

upin humans1HR 1.81

1 study
  1. Hypertension raises the risk of neovascular AMD in humans (HR 1.81, 95% CI 1.06–3.06).

    Humansunivariate analysis

    Chronic Hypertension and Conversion from Intermediate Age-Related Macular Degeneration (iAMD) to the Advanced Phenotypes · Ophthalmic epidemiology · 25 Aug 2026

Hypertension →

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OphthalmologyHumans

Genetically proxied CETP inhibition links to higher AMD risk

In drug-target Mendelian randomization, proxied CETP inhibition was associated with advanced AMD in Europeans (OR 1.45) and exudative AMD in East…In drug-target Mendelian randomization, proxied CETP inhibition was associated with advanced AMD in Europeans (OR 1.45) and exudative AMD in East Asians (OR 3.14).