AgingResearch.NewsJoin free

Microscopic polyangiitis

There are 3 papers on microscopic polyangiitis in aging research: 2 observational studies in people, 1 review. The newest story, Nov 4, 2026: “Rare autoimmune rheumatic diseases linked to higher death rates”.

Disease

3 papers study it3 more mention it4 findings

MeSH

1 new paper in 30 daysSee all 6 papers on microscopic polyangiitis

“found a preliminary negative correlation between anti-IgG of HSV1 and the risk of MPA (OR: 0.499, 95% CI: 0.361-0.692, p = 3.05E-05)”
Impact of Infection-Related Immune Responses on ANCA-Associated Vasculitis in Finns: A Mendelian Randomization StudyGenetics research2026doi:10.1155/genr/3406375
  • Humans2

Associations

4

MICA

upin humans1

1 study

  1. MICA is linked with a higher risk of microscopic polyangiitis in humans (mediated by upregulating DNAmAA) (Z = 3.702, p < 0.001, mediation effect = 72.1%).

    “MICA expression in NKR NK cells (Z = 3.702, p < 0.001, mediation effect = 72.1%) was associated with an increased risk of MPA by upregulating DNAmAA.”

    Humansmediated by upregulating DNAmAANKR NK cells

    Impact of Infection-Related Immune Responses on ANCA-Associated Vasculitis in Finns: A Mendelian Randomization Study

    Genetics research

More on MICA

MDC1

downin humans1

1 study

  1. MDC1 is linked with a lower risk of microscopic polyangiitis in humans (mediated by downregulating DNAmAA) (Z = -3.310, p = 0.001, mediation effect = 81.5%).

    “MDC1 in dendritic cells (Z = -3.310, p = 0.001, mediation effect = 81.5%) lowered the risk of MPA by downregulating DNAmAA.”

    Humansmediated by downregulating DNAmAAdendritic cells

    Impact of Infection-Related Immune Responses on ANCA-Associated Vasculitis in Finns: A Mendelian Randomization Study

    Genetics research

More on MDC1

HLA-C

downin humans1

1 study

  1. HLA-C is linked with a lower risk of microscopic polyangiitis in humans (mediated by downregulating DNAmAA) (Z = -2.921, p = 0.003, mediation effect = 82.2%).

    “HLA-C expression in CD8nc T cells (Z = -2.921, p = 0.003, mediation effect = 82.2%) and MDC1 in dendritic cells (Z = -3.310, p = 0.001, mediation effect = 81.5%) lowered the risk of MPA by downregulating DNAmAA.”

    Humansmediated by downregulating DNAmAACD8nc T cells

    Impact of Infection-Related Immune Responses on ANCA-Associated Vasculitis in Finns: A Mendelian Randomization Study

    Genetics research

More on HLA-C

Anti-HSV1 IgG

downin humans1OR 0.499

1 study

  1. Anti-HSV1 IgG is linked with a lower risk of microscopic polyangiitis in humans (Mendelian randomization) (OR: 0.499, 95% CI: 0.361-0.692).

    “found a preliminary negative correlation between anti-IgG of HSV1 and the risk of MPA (OR: 0.499, 95% CI: 0.361-0.692, p = 3.05E-05)”

    HumansMendelian randomization

    Impact of Infection-Related Immune Responses on ANCA-Associated Vasculitis in Finns: A Mendelian Randomization Study

    Genetics research

More on Anti-HSV1 IgG

Trial sponsors

Latest

Dec 2025: 0Jan 2026: 1Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 12 papers in 12 months
Rheumatology

Rare autoimmune rheumatic diseases linked to higher death rates

Age- and sex-adjusted death rates were 2.6 times the general population’s rate in 2013 and 2.3 times in 2020.Age- and sex-adjusted death rates were 2.6 times the general population’s rate in 2013 and 2.3 times in 2020.

Cohort studyPopulations
Paper

Related