Early-onset stroke

Disease1 paper4 findings

An in silico preprint links genetically predicted higher FN1 levels to lower early-onset stroke risk, whereas genetically predicted higher levels of ABO, F11 and F7 are linked to increased risk.

  • Humans1

Associations

4

F7

upin silico1

1 study
  1. F7 raises the risk of early-onset stroke in silico (ORs ~1.05-1.32 per SD).

    In silicogenetically predicted higher levels

    Identification of Plasma Protein Biomarkers for Early-Onset Stroke through Mendelian Randomization · medRxiv : the preprint server for health sciences · 15 Sep 2026 · Preprint

F7 →

ABO

upin silico1

1 study
  1. ABO raises the risk of early-onset stroke in silico (ORs ~1.05-1.32 per SD).

    In silicogenetically predicted higher levels

    Identification of Plasma Protein Biomarkers for Early-Onset Stroke through Mendelian Randomization · medRxiv : the preprint server for health sciences · 15 Sep 2026 · Preprint

ABO →

FN1

downin silico1

1 study
  1. FN1 lowers the risk of early-onset stroke in silico.

    In silicogenetically predicted higher levels

    Identification of Plasma Protein Biomarkers for Early-Onset Stroke through Mendelian Randomization · medRxiv : the preprint server for health sciences · 15 Sep 2026 · Preprint

FN1 →

F11

upin silico1

1 study
  1. F11 raises the risk of early-onset stroke in silico (ORs ~1.05-1.32 per SD).

    In silicogenetically predicted higher levels

    Identification of Plasma Protein Biomarkers for Early-Onset Stroke through Mendelian Randomization · medRxiv : the preprint server for health sciences · 15 Sep 2026 · Preprint

F11 →

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