Complex multimorbidity
Disease1 paper2 findings
- Humans1
Upstream
1hs-CRP/HDL-C ratio
mediatesin humans1
1 study
hs-CRP/HDL-C ratio
mediatesin humans1
hs-CRP/HDL-C ratio mediates complex multimorbidity in humans (5.17% of total effect, 95% CI 0.0001-0.0004).
Humansn = 8,246
Mediation of the association between sedentary behavior and complex multimorbidity by the hs-CRP/HDL-C ratio: Findings from NHANES 2015-2020 · Medicine · 18 Sep 2026
Associations
1Sedentary behavior
upin humans1OR 1.03Low certainty
1 study
Sedentary behavior
upin humans1OR 1.03Low certainty
Sedentary behavior raises the risk of complex multimorbidity in humans (OR 1.03, 95% CI 1.02-1.05).
Humansafter adjusting for potential confounding factorseach 1-hour increase in daily sedentary timen = 8,246
Mediation of the association between sedentary behavior and complex multimorbidity by the hs-CRP/HDL-C ratio: Findings from NHANES 2015-2020 · Medicine · 18 Sep 2026
Latest
5Sex-specific clinical history improves multimorbidity prediction
In about 155,000 PLCO cohort participants, adding sex-specific clinical history to models improved disease prediction and calibration, especially at…In about 155,000 PLCO cohort participants, adding sex-specific clinical history to models improved disease prediction and calibration, especially at higher multimorbidity burdens.