Comorbid obstructive sleep apnea and restless legs syndrome

1. Comorbid obstructive sleep apnea and restless legs syndrome is associated with hypertension in humans (aOR 2.64).

   “Hypertension was associated with COROSA and COMIROSA, with a larger estimate for COMIROSA (aOR 4.03 vs 2.64).”

   Humansmultivariable analysis

   Prevalence and correlates of comorbid obstructive sleep apnea and restless legs syndrome in a population-based study from Benin, West Africa

   medRxiv·12 Aug 2026Preprint

More on Hypertension

1. Obesity raises the risk of comorbid obstructive sleep apnea and restless legs syndrome in humans (aOR 3.83, 95% CI 1.75-8.31).

   “obesity (aOR 3.83, 95% CI: 1.75-8.31)”

   Humansmultivariable logistic regression

   Prevalence and correlates of comorbid obstructive sleep apnea and restless legs syndrome in a population-based study from Benin, West Africa

   medRxiv·12 Aug 2026Preprint

More on Obesity

1. Age raises the risk of comorbid obstructive sleep apnea and restless legs syndrome in humans (aOR 2.91, 95% CI 1.38-6.73).

   “Independent correlates were age 40-59 years (aOR 2.91, 95% CI 1.38-6.73)”

   Humans

   Prevalence and correlates of comorbid obstructive sleep apnea and restless legs syndrome in a population-based study from Benin, West Africa

   medRxiv·12 Aug 2026Preprint