Cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke

Disease

1 paper1 finding

  • Human trial1

Associations

1

Semaglutide

downin humans1HR 0.74

1 study
  1. Semaglutide lowers the risk of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in humans (HR 0.74, 95% CI 0.58 to 0.95).

    “The primary outcome occurred in 108 of 1648 patients (6.6%) in the semaglutide group and in 146 of 1649 patients (8.9%) in the placebo group (hazard ratio, 0.74; 95% confidence interval [CI], 0.58 to 0.95; P<0.001 for noninferiority).”

    Human trialtype 2 diabetes at high cardiovascular risk0.5 mg or 1.0 mg104 weeksn = 3,297

    Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes

    The New England journal of medicine15 Sep 2016

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