Void space
1 paper3 findings
- Humans1
Effects
1Failure load
downin humans1
1 study
Failure load
downin humans1
Void space decreases failure load in humans (-111.3 N, p = 0.006).
“reduction in failure load of 31.6 N at the radius (p = 0.073) and 111.3 N at the tibia (p = 0.006)”
Humanstibiamean follow-up of 6.8 ± 1.8 yearsn = 603
Localized bone deterioration predicts declining failure load and increased fracture risk
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA29 Oct 2025
Upstream
1Age
upin humans1
1 study
Age
upin humans1
age increases void space in humans (0.02% per year of age, p< 0.001).
“Void space increased by 0.02% per year of age (p< 0.001)”
Humansmean follow-up of 6.8 ± 1.8 yearsn = 603
Localized bone deterioration predicts declining failure load and increased fracture risk
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA29 Oct 2025
Associations
1Fracture risk
upin humans1
1 study
Fracture risk
upin humans1
Void space is associated with fracture risk in humans (0.5% increase per 1% increase in VS/TV, p< 0.01).
“A 1% increase in VS/TV was correlated with a 0.5% increase in fracture risk (p< 0.01)”
Humansmean follow-up of 6.8 ± 1.8 yearsn = 603
Localized bone deterioration predicts declining failure load and increased fracture risk
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA29 Oct 2025