Nephrology, Dialysis, Transplantation
Urine proteins may aid drug monitoring in kidney disease
A urine protein measure linked to kidney injury fell 46.3% from baseline after six weeks of atrasentan in people with chronic kidney disease.A urine protein measure linked to kidney injury fell 46.3% from baseline after six weeks of atrasentan in people with chronic kidney disease.
Randomized trial · 2,303 peopleBiomarkers
Who was studied2,303 people with chronic kidney disease, 1 year, against placebo
What changedUrinary epidermal growth factor declined less with dapagliflozin than placebo, a 9.7% relative difference
The catchMany urinary endothelin-1 measurements were below quantification limits, limiting detection of treatment effects