Trauma-Specific Frailty Index

1. Trauma-Specific Frailty Index was not clearly linked with mortality in humans (blunt trauma) (p>0.05).

   “When the patients who died and those who survived were compared at the 30th day after trauma, no significant difference was found in terms of BMI or TSFI (p>0.05).”

   Humansblunt trauma30 daysn = 382

   Relationships of the frailty index and geriatric trauma outcome score with mortality in geriatric trauma patients

   Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES·Mar 31, 2023

1. Trauma-Specific Frailty Index predicts mortality in humans (blunt trauma) (AUC 0.805 (95% CI: 0.725-0.885)).

   “Among the frailty scores, TSFI proved to be superior in predicting mortality, achieving an AUC of 0.805 (95% CI: 0.725-0.885)”

   Humansblunt trauman = 350

   Predicting mortality and intensive care needs in geriatric trauma patients: A ROC analysis of frailty and trauma scoring systems

   European journal of trauma and emergency surgery : official publication of the European Trauma Society·Jul 21, 2025

2. Trauma-Specific Frailty Index is linked with a higher risk of mortality in humans (geriatric trauma patients) (higher odds per 0.1 increase).

   “every 0.1 increase in the TSFI score was independently associated with higher odds of index-admission mortality and major complications”

   Humansgeriatric trauma patientsevery 0.1 increase in the TSFI scoren = 1,321

   It is not all black and white: The effect of increasing severity of frailty on outcomes of geriatric trauma patients

   The journal of trauma and acute care surgery·Nov 22, 2023

3. Trauma-Specific Frailty Index is associated with mortality in humans (geriatric trauma patients) (p < 0.05).

   “In addition, frailty was significantly associated with higher adjusted odds of mortality, major complications, readmissions, and fall recurrence at 3 months postdischarge ( p < 0.05).”

   Humansgeriatric trauma patients3 months postdischargen = 1,321

   Prospective validation and application of the Trauma-Specific Frailty Index: Results of an American Association for the Surgery of Trauma multi-institutional observational trial

   The journal of trauma and acute care surgery·Oct 17, 2022

4. Trauma-Specific Frailty Index predicts mortality in humans (geriatric trauma patients) (aOR 1.93, p = 0.018).

   “Compared with nonfrail patients, frail patients had significantly higher odds of mortality (adjusted odds ratio [aOR], 1.93; p = 0.018)”

   Humansgeriatric trauma patientsn = 1,321

   Prospective validation and application of the Trauma-Specific Frailty Index: Results of an American Association for the Surgery of Trauma multi-institutional observational trial

   The journal of trauma and acute care surgery·Oct 17, 2022

1. Trauma-Specific Frailty Index is linked with a higher risk of accidental falls in humans (geriatric trauma patients) (higher odds per 0.1 increase).

   “readmissions, major complications, and fall recurrence”

   Humansgeriatric trauma patientsevery 0.1 increase in the TSFI scoren = 1,116

   It is not all black and white: The effect of increasing severity of frailty on outcomes of geriatric trauma patients

   The journal of trauma and acute care surgery·Nov 22, 2023

1. Trauma-Specific Frailty Index is linked with a higher risk of hospital readmission in humans (geriatric trauma patients) (higher odds per 0.1 increase).

   “3 months postdischarge mortality, readmissions, major complications, and fall recurrence”

   Humansgeriatric trauma patientsevery 0.1 increase in the TSFI scoren = 1,116

   It is not all black and white: The effect of increasing severity of frailty on outcomes of geriatric trauma patients

   The journal of trauma and acute care surgery·Nov 22, 2023

1. Trauma-Specific Frailty Index is linked with a higher risk of postdischarge mortality in humans (geriatric trauma patients) (higher odds per 0.1 increase).

   “every 0.1 increase in the TSFI score was independently associated with higher odds of index-admission mortality and major complications, and 3 months postdischarge mortality”

   Humansgeriatric trauma patientsevery 0.1 increase in the TSFI scoren = 1,116

   It is not all black and white: The effect of increasing severity of frailty on outcomes of geriatric trauma patients

   The journal of trauma and acute care surgery·Nov 22, 2023

1. Trauma-Specific Frailty Index predicts discharge to rehabilitation centers or skilled nursing facilities in humans (geriatric trauma patients) (aOR 1.98, p < 0.001).

   “and discharge to rehab/SNFs (aOR, 1.98; p < 0.001).”

   Humansgeriatric trauma patientsn = 1,321

   Prospective validation and application of the Trauma-Specific Frailty Index: Results of an American Association for the Surgery of Trauma multi-institutional observational trial

   The journal of trauma and acute care surgery·Oct 17, 2022

1. Trauma-Specific Frailty Index predicts major complications in humans (geriatric trauma patients) (aOR 3.55, p < 0.001).

   “major complications (aOR, 3.55; p < 0.001)”

   Humansgeriatric trauma patientsn = 1,321

   Prospective validation and application of the Trauma-Specific Frailty Index: Results of an American Association for the Surgery of Trauma multi-institutional observational trial

   The journal of trauma and acute care surgery·Oct 17, 2022

1. Geriatric trauma frailty index is associated with Trauma-Specific Frailty Index in humans (geriatric trauma) (ICC: 0.407, 95% CI: 0.227, 0.562, kappa: 0.460).

   “fair consistency with the TSFI (ICC: 0.407, 95% CI: 0.227, 0.562, kappa: 0.460, 95% CI: 0.239, 0.672)”

   Humansgeriatric trauman = 101

   Validating the agreement between the geriatric trauma frailty index and four published frailty scores in the Chinese geriatric trauma population

   BMC geriatrics·Mar 4, 2022

More on Geriatric trauma frailty index

1. Upper-extremity frailty model is associated with Trauma-Specific Frailty Index in humans (hospitalized after traumatic ground-level falls) (r = 0.72).

   “A high agreement (r = 0.72, p < 0.0001) was observed between TSFI score and the UEF model”

   Humanshospitalized after traumatic ground-level fallsn = 101

   Assessing Upper-Extremity Motion: An Innovative, Objective Method to Identify Frailty in Older Bed-Bound Trauma Patients

   Journal of the American College of Surgeons·May 4, 2016

More on Upper-extremity frailty model