International Journal of Molecular Sciences
Solid and blood cancers differ in how one gene is altered
Protein-shortening mutations accounted for 34.2% of samples with the altered gene in solid cancers, versus 24.4% in blood cancers.Protein-shortening mutations accounted for 34.2% of samples with the altered gene in solid cancers, versus 24.4% in blood cancers.
Meta-analysisMechanisms
Who was studiedSamples from solid and blood cancers, against blood cancers
What changedProtein-shortening TP53 mutations were more common in solid tumors: 34.2% versus 24.4% in blood cancers
The catchProtein retention was inferred from mutation class, without directly measuring mutant protein