Tight junction-related gene expression

Chronological ageing has no effect on tight junction-related gene expression in humans.

“Expression levels of all four investigated tight junction-related genes in the gastric epithelium, in the duodenal epithelium, and in the epithelium of the ascending and descending colon were not affected by chronological ageing.”

Humansgastrointestinal epithelium

Impact of chronological ageing on tight junction-related gene expression at the human gastrointestinal epithelium: An exploratory study

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences·19 Mar 2026