Thoracic vertebral bone mineral density

Biomarker1 paper4 findings

In one study of the MESA human cohort without clinically recognised cardiovascular disease, thoracic vertebral bone mineral density predicts cognitive function, Cognitive Abilities Screening Instrument scores, white matter fractional anisotropy and white matter hyperintensity volume.

  • Humans1

Associations

4

White matter fractional anisotropy

downin humans1

1 study
  1. Thoracic vertebral bone mineral density predicts white matter fractional anisotropy in humans (β = -0.048 SD/year).

    HumansMESA cohort without clinically recognized CVDanterior limb of the internal capsulen = 405

    Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026

White matter fractional anisotropy →

White matter hyperintensity volume

upin humans1

1 study
  1. Thoracic vertebral bone mineral density predicts white matter hyperintensity volume in humans (β = 12.8%/year).

    HumansMESA cohort without clinically recognized CVDcorpus callosumn = 408

    Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026

White matter hyperintensity volume →

Cognitive Abilities Screening Instrument

downin humans1

1 study
  1. Thoracic vertebral bone mineral density predicts Cognitive Abilities Screening Instrument in humans (β = -0.320/year).

    HumansMESA cohort without clinically recognized CVDbrainn = 675

    Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026

Cognitive Abilities Screening Instrument →

Cognitive function

downin humans1

1 study
  1. Thoracic vertebral bone mineral density predicts cognitive function in humans (β = -0.025 SD/year).

    HumansMESA cohort without clinically recognized CVDbrainn = 639

    Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026

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