Thoracic vertebral bone mineral density
Biomarker1 paper4 findings
In one study of the MESA human cohort without clinically recognised cardiovascular disease, thoracic vertebral bone mineral density predicts cognitive function, Cognitive Abilities Screening Instrument scores, white matter fractional anisotropy and white matter hyperintensity volume.
- Humans1
Associations
4White matter fractional anisotropy
downin humans1
1 study
White matter fractional anisotropy
downin humans1
Thoracic vertebral bone mineral density predicts white matter fractional anisotropy in humans (β = -0.048 SD/year).
HumansMESA cohort without clinically recognized CVDanterior limb of the internal capsulen = 405
Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026
White matter hyperintensity volume
upin humans1
1 study
White matter hyperintensity volume
upin humans1
Thoracic vertebral bone mineral density predicts white matter hyperintensity volume in humans (β = 12.8%/year).
HumansMESA cohort without clinically recognized CVDcorpus callosumn = 408
Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026
Cognitive Abilities Screening Instrument
downin humans1
1 study
Cognitive Abilities Screening Instrument
downin humans1
Thoracic vertebral bone mineral density predicts Cognitive Abilities Screening Instrument in humans (β = -0.320/year).
HumansMESA cohort without clinically recognized CVDbrainn = 675
Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026
Cognitive function
downin humans1
1 study
Cognitive function
downin humans1
Thoracic vertebral bone mineral density predicts cognitive function in humans (β = -0.025 SD/year).
HumansMESA cohort without clinically recognized CVDbrainn = 639
Deep Learning-derived Bone Mineral Density and Longitudinal White Matter Microstructure and Cognitive Decline: Multi-Ethnic Study of Atherosclerosis · Radiology · 1 Sep 2026