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Thin spine density

Biomarker

2 papers study it3 findings

  • Animals2

Associations

3

Working memory performance

upin rhesus monkeys1

1 study

  1. Thin spine density is associated with working memory performance in rhesus monkeys.

    “thin spine density positively correlates with delayed response performance in aged monkeys.”

    Animalsarea 7amale and females

    Selective Loss of Thin Spines in Area 7a of the Primate Intraparietal Sulcus Predicts Age-Related Working Memory Impairment

    The Journal of neuroscience : the official journal of the Society for Neuroscience

Age

downin rhesus monkeys1

1 study

  1. Age is associated with thin spine density in rhesus monkeys.

    “Area 7a shows age-related loss of thin spines”

    Animalsarea 7amale and females

    Selective Loss of Thin Spines in Area 7a of the Primate Intraparietal Sulcus Predicts Age-Related Working Memory Impairment

    The Journal of neuroscience : the official journal of the Society for Neuroscience

Spatial memory performance

mixedin mice1

1 study

  1. Thin spine density is associated with spatial memory performance in mice.

    “the density of thin spines significantly correlated with spatial memory performance.”

    AnimalsCA1 pyramidal cell dendrites

    Loss of thin spines and small synapses contributes to defective hippocampal function in aged mice

    Neurobiology of aging

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