System-specific metabolomic aging clock

Biomarker1 paper3 findings

Humans1

Associations

3

Cognitive function

upin humans1

1 study

System-specific metabolomic aging clock is associated with cognitive function in humans.
“These same subgroups also showed more favorable cognitive outcomes and reduced mortality risk”
Humansin subgroups with favorable NVIs
System-Specific Metabolomic Clocks Reveal Aging Heterogeneity and Links to Diet, Cognition, Mortality · GSA 2025 abstract · 31 Dec 2025

Mortality

downin humans1

1 study

System-specific metabolomic aging clock is associated with mortality in humans.
“These same subgroups also showed more favorable cognitive outcomes and reduced mortality risk”
Humansin subgroups with favorable NVIs
System-Specific Metabolomic Clocks Reveal Aging Heterogeneity and Links to Diet, Cognition, Mortality · GSA 2025 abstract · 31 Dec 2025

Nutrient Variety Index

mixedin humans1

1 study

Nutrient Variety Index is associated with system-specific metabolomic aging clock in humans.
“We found that several subgroups displayed significant associations with multiple NVIs, particularly those reflecting balanced intake of carbohydrates.”
Humans
System-Specific Metabolomic Clocks Reveal Aging Heterogeneity and Links to Diet, Cognition, Mortality · GSA 2025 abstract · 31 Dec 2025

Nutrient Variety Index →

Latest

1

GSA 2025 AbstractHumans3 Jan

System-Specific Metabolomic Clocks Reveal Aging Heterogeneity and Links to Diet, Cognition, Mortality