Aging Cell
Restoring a protein partly improves heart function in mice
Experiments in mice producing a progeria-linked protein in heart muscle cells found that restoring an RNA-marking protein partly reduced abnormal heart changes.Experiments in mice producing a progeria-linked protein in heart muscle cells found that restoring an RNA-marking protein partly reduced abnormal heart changes.
Mouse studyMechanisms
Who was studiedMice with cardiomyocyte-specific progerin expression, 2 months
What changedRestoring METTL14 reduced heart scarring in progeria mice compared with control-vector-treated mice
The catchReduced heart scarring is not a direct measure of improved heart pumping