Synchrony–scaling relationship

Biomarker

1 paper1 finding

  • In silico1

Associations

1

Age

mixedin humans1

1 study
  1. Age is associated with synchrony–scaling relationship in humans.

    “The synchrony–scaling relationship remains stable during resting-state activity but progressively shifts during naturalistic tasks across the lifespan”

    HumansResting-state activity versus naturalistic tasks across the lifespanbrain

    A generalized scaling law reveals synchrony-driven reorganization of brain dynamics across the human lifespan

    bioRxiv (Cold Spring Harbor Laboratory)16 Jan 2026Preprint

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PLOS Computational Biology

Healthy aging linked to lower brain scaling exponent in humans

In three cohorts totaling 840 people aged 18–88, fMRI analyses linked a lower scaling exponent during healthy aging to coordinated brain activity.In three cohorts totaling 840 people aged 18–88, fMRI analyses linked a lower scaling exponent during healthy aging to coordinated brain activity.

Cohort study of 840 peopleMechanisms