Preprints.org
Age-linked RNA processing differs in human brain and body
The spread of age-linked effects at the same RNA joining sites was 2.0–2.8 times as wide in brain as in body tissues from the same donors.The spread of age-linked effects at the same RNA joining sites was 2.0–2.8 times as wide in brain as in body tissues from the same donors.
Preprint: cross-sectional · 382 peopleMechanisms
Who was studied382 human donors contributing brain and body tissues
What changedAge-linked RNA splicing effects were 2.0–2.8 times as variable in brain as in body tissues from the same donors
The catchYounger body-tissue donors disproportionately died on ventilators, mixing age effects with circumstances of death