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SFRP2-positive fibroblast abundance

Biomarker

1 paper2 findings

  • Humans1

Associations

2

Poor prognosis in basal cell carcinoma

upin humans1

1 study

  1. SFRP2-positive fibroblast abundance is associated with poor prognosis in basal cell carcinoma in humans.

    “a previously unrecognized fibroblast subtype marked by SFRP2 expression, which expands with age and is associated with poor prognosis in basal cell carcinoma.”

    Humansbasal cell carcinomaskin

    Integrated Single-Cell and Spatial Transcriptomic Analysis Reveals an Aging-Associated Fibroblast Subtype Linked to Tumor Progression in Human Skin

    bioRxiv (Cold Spring Harbor Laboratory)12 Jul 2025Preprint

Age

upin humans1

1 study

  1. Age is associated with SFRP2-positive fibroblast abundance in humans.

    “we identified a previously unrecognized fibroblast subtype marked by SFRP2 expression, which expands with age”

    Humansskin

    Integrated Single-Cell and Spatial Transcriptomic Analysis Reveals an Aging-Associated Fibroblast Subtype Linked to Tumor Progression in Human Skin

    bioRxiv (Cold Spring Harbor Laboratory)12 Jul 2025Preprint

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