Secreted klotho

Biomarker

2 papers2 findings

  • Humans1

Upstream

1

KL

upin human cells1downin human cells1

1 study
  1. KL increases secreted klotho in human cells (2.9-fold increase).

    “extracellular levels of the S370 form are increased 2.9-fold”

    CellsS370 form

    Association of human aging with a functional variant of klotho

    Proceedings of the National Academy of Sciences of the United States of America15 Jan 2002

  2. KL decreases secreted klotho in human cells (6-fold reduction).

    “secreted levels of klotho harboring V352 are reduced 6-fold”

    CellsV352 form

    Association of human aging with a functional variant of klotho

    Proceedings of the National Academy of Sciences of the United States of America15 Jan 2002

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