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Sarcopenia index polygenic risk score

There is 1 paper on sarcopenia index polygenic risk score in aging research: 1 observational study in people. The newest story, Nov 9, 2026: “Muscle-related genetic score linked to lower liver disease odds”.

Biomarker

1 paper studies it6 findings

1 new paper in 30 daysSee all 1 papers on sarcopenia index polygenic risk score

“SI PRS was associated with reduced risks of NAFLD (OR = 0.97 [95% CI 0.95–0.99], p = 0.028)”
Sarcopenia Index Predicts the Risk of Liver Diseases: Genome-Wide Association Study and Polygenic Risk Score-Based Analyses in UK Biobank CohortBiomedicines2026doi:10.3390/biomedicines14112564
  • Humans1

Effects

1

Alcoholic liver disease

no changein humans1OR 0.96

1 study

  1. Sarcopenia index polygenic risk score was not clearly linked with alcoholic liver disease in humans (OR 0.96, 95% CI 0.92–1.02; p = 0.120).

    “but not alcoholic liver disease (OR = 0.96 [95% CI 0.92–1.02], p = 0.120)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

More on Alcoholic liver disease

Associations

4

Metabolic dysfunction-associated steatotic liver disease

downin humans1OR 0.97–0.98

1 study

  1. Sarcopenia index polygenic risk score is associated with metabolic dysfunction-associated steatotic liver disease in humans (OR 0.98, 95% CI 0.97–0.99).

    “MASLD (OR = 0.98 [95% CI 0.97–0.99], p < 0.001)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

  2. Sarcopenia index polygenic risk score is associated with metabolic dysfunction-associated steatotic liver disease in humans (OR 0.97, 95% CI 0.95–0.99).

    “SI PRS was associated with reduced risks of NAFLD (OR = 0.97 [95% CI 0.95–0.99], p = 0.028)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

More on Metabolic dysfunction-associated steatotic liver disease

Liver cancer

downin humans1OR 0.98

1 study

  1. Sarcopenia index polygenic risk score is associated with liver cancer in humans (OR 0.98, 95% CI 0.96–1.00; p = 0.037).

    “liver cancer (OR = 0.98 [95% CI 0.96–1.00], p = 0.037)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

More on Liver cancer

End-stage liver disease

downin humans1OR 0.97

1 study

  1. Sarcopenia index polygenic risk score is associated with end-stage liver disease in humans (OR 0.97, 95% CI 0.94–0.99).

    “ESLD (OR = 0.97 [95% CI 0.94–0.99], p = 0.012)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

More on End-stage liver disease

Liver fibrosis

downin humans1OR 0.93

1 study

  1. Sarcopenia index polygenic risk score is associated with liver fibrosis in humans (OR 0.93, 95% CI 0.90–0.96).

    “liver fibrosis (OR = 0.93 [95% CI 0.90–0.96], p < 0.001)”

    Humansn = 389,804

    Muscle-related genetic score linked to lower liver disease odds

    Biomedicines

More on Liver fibrosis

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
Biomedicines

Muscle-related genetic score linked to lower liver disease odds

Higher genetic scores were linked to lower odds of nonalcoholic fatty liver disease, with an odds ratio of 0.97 compared with lower scores.Higher genetic scores were linked to lower odds of nonalcoholic fatty liver disease, with an odds ratio of 0.97 compared with lower scores.

Genetic association · 389,804 peopleLiver disease
Paper

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