ESC Congress 2026 Abstract
Immune cell group helps repair hearts in newborn mice
Experiments in newborn mice found that removing these cells reduced heart muscle cell multiplication and worsened inflammation and scarring after heart attacks.Experiments in newborn mice found that removing these cells reduced heart muscle cell multiplication and worsened inflammation and scarring after heart attacks.
Mouse studyBlood and immune system
Who was studiedNeonatal mice
What changedGenetically removing S100A8-marked macrophages impaired heart regeneration and reduced heart muscle cell multiplication in newborn mice
The catchHeart repair was assessed by cell proliferation and fibrosis; heart function was not measured