Retinal BioAgeGap

1. Hypertension is associated with retinal BioAgeGap in humans (+0.08 versus −0.52 years with versus without hypertension).

   “a negative retinal BioAge was no longer found among those with hypertension (≥130/80mmHg) compared to those without (+0.08 vs -0.52 years, P<0.001).”

   HumansIndividuals with high cardiovascular health scores; hypertension defined as ≥130/80 mmHgretina

   Impact of Life’s Essential 8 Cardiovascular Health Score and Hypertension on Retinal Biological Aging

   medRxiv·18 Oct 2025Preprint

More on Hypertension

1. Life's Essential 8 cardiovascular health score is associated with retinal BioAgeGap in humans (−0.65 years; highest versus lowest quartile: −0.36 vs. +0.30 years).

   “Participants in the highest CVH quartile were shown to have a negative retinal BioAgeGap while the lowest CVH quartile had a positive retinal BioAgeGap”

   HumansHighest versus lowest cardiovascular health quartileretinan = 4,887

   Impact of Life’s Essential 8 Cardiovascular Health Score and Hypertension on Retinal Biological Aging

   medRxiv·18 Oct 2025Preprint

More on Life's Essential 8 cardiovascular health score