Regional trinucleotide composition

Regional trinucleotide composition predicts lifespan in silico (Predictive R2 0.594 for ln(lifespan); mean absolute error 5.24 years; median fold error 1.91).

“Fixed-holdout predictions achieved a predictive R2 of 0.594 for ln(lifespan), a mean absolute error of 5.24 years, and a median fold error of 1.91.”

In silicofixed-holdout evaluationn = 139

Lifespan prediction in protostomes from trinucleotide composition

Research Square·Oct 16, 2026Preprint