Prior depressive-symptom burden

1. Prior depressive-symptom burden raises the risk of incident heart disease in humans.

   “both prior burden and current deviation were associated with incident heart disease, with a larger coefficient for prior burden.”

   HumansHRS cohort

   Prior depressive-symptom burden, current deviation from personal history, and incident heart disease: a three-cohort longitudinal study

   Research Square·15 Aug 2026Preprint

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