Research Square

Prior depressive-symptom burden, current deviation from personal history, and incident heart disease: a three-cohort longitudinal study

Preprint: cohort study of 26,489 peoplePopulations

Independent replication

Abstract

Background Depressive symptoms are associated with cardiovascular risk, but epidemiologic analyses commonly use a single baseline or current score even when repeated assessments are available. A current score may reflect long-standing symptom burden, recent departure from personal history, or both.

The paper

Anhui University of Traditional Chinese Medicine

Research Square, 15 Aug 2026, CC BY, Preprint, not peer-reviewed

doi.org/10.21203/rs.3.rs-10355469/v1