PPG-derived heart age

PPG-derived heart age predicts chronological age in humans (Mean absolute error 5.895 years; Pearson r=0.819).

“the PPG-only model achieved subject-level mean absolute errors of 5.895 years (Pearson r=0.819) in the PWV cohort”

HumansExternal validation in the PWV cohort

Smartwatch Photoplethysmography-Derived Heart Age via ECG-Guided Cross-Modal Pretraining as a Digital Biomarker of Vascular Aging

arXiv (Cornell University)·3 Aug 2026Preprint