Polygenic BMI score

1. Surgery is associated with polygenic BMI score in humans (b=-0.002, p<.001).

   “with each increase in the number of hip, knee, heart, cataract, or back surgeries during 2017 there was and associated decline in physical capacity (walking 3 or more blocks, b=-0.14, p<.001) and polygenic BMI scores (b=-0.002, p<.001”

   Humansn = 2,827

   NIH Resilience Model: Longitudinal Effects of Surgery on Genetics, Physical Capacity & Chronic Conditions

   GSA 2025 abstract·31 Dec 2025

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