Plasma atherosclerosis index

1. Flavonoids decrease plasma atherosclerosis index in humans (from 0.103 in Q1 to 0.066 in Q4).

   “Adjusted mean AIP decreased progressively across quartiles of total flavonoid intake, from 0.103 in Q1 to 0.066 in Q4 (P for trend < 0.001).”

   Humansadjusted mean across quartiles

   Total Flavonoid Intake, Plasma atherosclerosis index, and Risk of Incident ASCVD: A Prospective Cohort Study from the UK Biobank

   Research Square·13 Aug 2026Preprint

More on Flavonoids

1. Plasma atherosclerosis index mediates atherosclerotic cardiovascular disease in humans (11.3% proportion mediated).

   “Mediation analysis suggested a small indirect effect through AIP, with an estimated proportion mediated of 11.3%.”

   Humansflavonoid intake to ASCVD risk

   Total Flavonoid Intake, Plasma atherosclerosis index, and Risk of Incident ASCVD: A Prospective Cohort Study from the UK Biobank

   Research Square·13 Aug 2026Preprint

More on Atherosclerotic cardiovascular disease

1. Plasma atherosclerosis index raises the risk of atherosclerotic cardiovascular disease in humans (19.8% higher risk (HR = 1.198, 95% CI: 1.164–1.233)).

   “each 1-SD increase in AIP was associated with a 19.8% higher risk of ASCVD (HR = 1.198, 95% CI: 1.164–1.233).”

   Humanseach 1-SD increase

   Total Flavonoid Intake, Plasma atherosclerosis index, and Risk of Incident ASCVD: A Prospective Cohort Study from the UK Biobank

   Research Square·13 Aug 2026Preprint

More on Atherosclerotic cardiovascular disease