Pkm expression

aging and age-related macular degeneration is associated with Pkm expression in mice.

“Our findings reveal an upregulation in PKM2 and ALDOC expression, accompanied by increased pyruvate kinase activity, in the aged and AMD mouse RPE.”

Animalsaged mice and experimentally induced AMD mouse modelretinal pigment epithelium

Age-Related Changes in the Glycolytic Enzymes of M2-Isoform of Pyruvate Kinase and Fructose-1,6-Bisphosphate Aldolase: Implications to Age-Related Macular Degeneration

Aging and disease·13 May 2024