PhysioRisk

Biomarker1 paper2 findings

  • Humans1

Associations

2

Chronological age

upin humans1

1 study
  1. PhysioRisk is associated with chronological age in humans (r=0.106).

    Humans

    Separating age and physiology can preserve death-risk ranking · Research Square · 6 Oct 2026 · Preprint

Mortality

upin humans1HR 1.387

1 study
  1. PhysioRisk predicts mortality in humans (HR 1.387, 95% CI 1.338–1.439 per standard deviation).

    HumansInternal temporal validation in 2011–2016; per validation-cohort standard deviationn = 6,739

    Separating age and physiology can preserve death-risk ranking · Research Square · 6 Oct 2026 · Preprint

Latest

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Research SquareHumansPreprint

Separating age and physiology can preserve death-risk ranking

The combined score reached 0.843 on a measure of death-risk ranking, exceeding the age-and-sex score by 0.016 in 6,739 validation participants.The combined score reached 0.843 on a measure of death-risk ranking, exceeding the age-and-sex score by 0.016 in 6,739 validation participants.