PGS000125

1. PGS000125 predicts prediabetes in humans (AUC 0.583, 95% CI 0.534–0.630).

   “discrimination was weak (area under the receiver operating characteristic curve 0.583; bootstrap 95% confidence interval 0.534–0.630).”

   Humansfemalesn = 540

   Genome-wide association and polygenic risk score analysis of prediabetes in South Indian women · Research Square · 2 Sep 2026 · Preprint

2. PGS000125 raises the risk of prediabetes in humans (OR 1.38, 95% CI 1.16–1.65).

   “Each standard-deviation increase was associated with 1.38-fold higher odds of prediabetes (95% confidence interval 1.16–1.65; P = 0.00032)”

   Humansper SD increase in PGS000125femalesn = 540

   Genome-wide association and polygenic risk score analysis of prediabetes in South Indian women · Research Square · 2 Sep 2026 · Preprint

Prediabetes →