Pentosidine accumulation

Age is associated with pentosidine accumulation in humans.

“From the mid-30s onward, staining became more frequent, with both staining intensity as well as the expansion of the areas with positive findings increasing with age.”

Humansepiglottisn = 54

Immunohistological detection of pentosidine in the epiglottis:A contribution to molecular age estimation

International journal of legal medicine·18 Mar 2026