What does the research say about Parp1 and Sirt1 transcription?

Parp1 and Sirt1 transcription

There is 1 paper on Parp1 and Sirt1 transcription in aging research: none in people yet, 1 in animals. The newest story, Nov 4, 2026: “Cream did not protect mouse skin from repeated ultraviolet damage”.

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1 paper studies it1 finding

1 new paper in 30 daysSee all 1 papers on Parp1 and Sirt1 transcription

Animals1

Interventions

Nicotinamide mononucleotide

no changein mice1

1 study

Nicotinamide mononucleotide showed no clear effect on Parp1 and Sirt1 transcription in mice (chronic UVB exposure).
“In contrast, no increase in Parp1 and Sirt1 was observed at the transcriptional level in the NMN group.”
Animalschronic UVB exposurecreamskin5%females
Cream did not protect mouse skin from repeated ultraviolet damage
International journal of molecular sciencesOct 31, 2026

Latest

1 paper in 12 months

International Journal of Molecular SciencesNov 4

Cream did not protect mouse skin from repeated ultraviolet damage

Female mice given 5% nicotinamide mononucleotide cream after ultraviolet B exposure three times weekly through week 25 showed no protection against skin damage.Female mice given 5% nicotinamide mononucleotide cream after ultraviolet B exposure three times weekly through week 25 showed no protection against skin damage.

Mouse studySkin

Paper

Parp1 and Sirt1 transcription

Interventions

Latest

Cream did not protect mouse skin from repeated ultraviolet damage

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