Paraspinal muscle attenuation

1. Paraspinal muscle attenuation is associated with bone mineral density in humans (176 mg/cm3 vs 205 mg/cm3).

   Humansquartile 1 vs quartiles 2-4paraspinal musclen = 1,316

   Opportunistic Chest CT Paraspinal Muscle Biomarkers to Predict Longitudinal Thoracic Vertebral Bone Mineral Density Loss: Results from MESA · Radiology · 1 Sep 2026

2. Paraspinal muscle attenuation predicts bone mineral density in humans (adjusted R2, 0.27 vs 0.20).

   Humanslongitudinal analysis (2010 to 2016)paraspinal musclen = 1,316

   Opportunistic Chest CT Paraspinal Muscle Biomarkers to Predict Longitudinal Thoracic Vertebral Bone Mineral Density Loss: Results from MESA · Radiology · 1 Sep 2026

Bone mineral density →

1. Paraspinal muscle attenuation predicts vertebral fracture in humans (AUC 0.82 vs 0.76).

   Humansbeyond BMD aloneparaspinal musclen = 1,316

   Opportunistic Chest CT Paraspinal Muscle Biomarkers to Predict Longitudinal Thoracic Vertebral Bone Mineral Density Loss: Results from MESA · Radiology · 1 Sep 2026

Vertebral fracture →