OxPC accumulation

There is 1 paper on OxPC accumulation in aging research: none in people yet, 1 in animals.

1 paper studies it1 finding

See all 1 papers on OxPC accumulation

Animals1

Upstream

1

IL-1 signaling

upin mice1

1 study

IL-1 signaling increases OxPC accumulation in mice (shown by Casp1/Casp4 deficiency and IL-1R1 blockade).
“indicate that IL-1β signaling contributes to chronic OxPC accumulation and neurodegeneration”
Animalsshown by Casp1/Casp4 deficiency and IL-1R1 blockadeCNS
Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling
Nature neuroscienceDec 1, 2025

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Nature NeuroscienceDec 2

Oxidized phosphatidylcholines deposition drives chronic neurodegeneration in a mouse model of progressive multiple sclerosis via IL-1β signaling

Experiments in miceIL-1 signaling