Nonlinear structural-functional coupling

Older age is associated with nonlinear structural-functional coupling in humans.

“Our results demonstrated that the young group exhibited significantly stronger NGC-based SFC compared to the sex-matched older group.”

HumansHealthy participants; sex-matched age-group comparisonbrainn = 227

Mapping Whole-Brain Nonlinear Structure-Function Dynamics in Aging via Neural Granger Causality

Brain topography·23 Jun 2026