Alzheimer's & Dementia
Amyloid clumps without fibers linked to altered signaling in mice
Experiments in genetically altered mice aged 2 to 24 months linked clumps that do not form fibers to abnormal signaling without detectable inflammation.Experiments in genetically altered mice aged 2 to 24 months linked clumps that do not form fibers to abnormal signaling without detectable inflammation.
Mouse studySynaptic transmission
Who was studiedMale and female Dutch mice, against mice without the genetic alteration
What changedDutch mice had abnormalities in short-term signaling compared with mice without the genetic alteration
The catchSymptom improvement from removing all forms of amyloid beta was not measured