Mutations detected only in unfractionated marrow

There is 1 paper on mutations detected only in unfractionated marrow in aging research: 1 observational study in people. The newest story, Oct 29, 2026: “Stem-cell mutations predicted blood cancer relapse after transplant”.

Biomarker

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“Mutations detected only in unfractionated marrow did not predict relapse.”
Persistent Malignant Stem Cells Drive Relapse After Transplantation in the Myelodysplastic NeoplasmsbioRxiv2026doi:10.64898/2026.10.28.761431
  • Humans1

Effects

1

Post-transplant relapse

no changein humans1

1 study
  1. Mutations detected only in unfractionated marrow was not clearly linked with post-transplant relapse in humans (myelodysplastic neoplasms after allogeneic transplantation).

    “Mutations detected only in unfractionated marrow did not predict relapse.”

    Humansmyelodysplastic neoplasms after allogeneic transplantationbone marrow

    Stem-cell mutations predicted blood cancer relapse after transplant

    bioRxivPreprint

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bioRxiv

Stem-cell mutations predicted blood cancer relapse after transplant

Relapse was reported in 95.7% of patients with detected stem-cell mutations versus 30.3% without them in an observational cohort after transplantation.Relapse was reported in 95.7% of patients with detected stem-cell mutations versus 30.3% without them in an observational cohort after transplantation.

Preprint: cohort studyBiomarkers