Multimorbidity score
Biomarker1 paper2 findings
- In silico1
Effects
1Survival prediction
upin silico1
1 study
Survival prediction
upin silico1
Multimorbidity score improves survival prediction in silico (C-index up to 0.91).
In silicoin real UK Biobank data
Distilled language models improve multimorbidity scoring · medRxiv : the preprint server for health sciences · 21 Sep 2026 · Preprint
Associations
1SNP heritability
upin silico1
1 study
SNP heritability
upin silico1
Multimorbidity score is associated with SNP heritability in silico (h2 ≈ 0.05).
In silicoin real UK Biobank data
Distilled language models improve multimorbidity scoring · medRxiv : the preprint server for health sciences · 21 Sep 2026 · Preprint
Latest
2Language model multimorbidity score predicts mortality in adults
Across eight external cohorts, the score yielded C-indices of 0.67 to 0.86, outperforming recalibrated conventional comorbidity indices by absolute…Across eight external cohorts, the score yielded C-indices of 0.67 to 0.86, outperforming recalibrated conventional comorbidity indices by absolute gains of 0.12 to 0.21.
Distilled language models improve multimorbidity scoring
Compact models trained on synthetic UK Biobank cohorts predicted patient survival with concordance indices reaching 0.91 without exposing real…Compact models trained on synthetic UK Biobank cohorts predicted patient survival with concordance indices reaching 0.91 without exposing real clinical data.