Multidomain vulnerability burden

1. Multidomain vulnerability burden raises the risk of cardiovascular disease in humans (pooled HR 1.210, 95% CI 1.113–1.316).

   “The pooled HR was 1.210 (95% CI 1.113–1.316; 95% prediction interval 1.051–1.393).”

   Humanswithout baseline heart disease or stroken = 31,535

   Multidomain vulnerability burden and incident cardiovascular disease among middle-aged and older adults: evidence from three longitudinal ageing cohorts

   Research Square·6 Aug 2026Preprint

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