There are 8 papers on modified creatinine index in aging research: 7 observational studies in people, 1 review.
8 papers study it2 more mention it8 findings
See all 10 papers on modified creatinine index
“Lower modified creatinine index was associated with increased risk for bone fracture in male and female hemodialysis patients.”
- Humans7
Associations
6Mortality
downin humans1upin humans1HR 2.51
2 studies
Mortality
downin humans1upin humans1HR 2.51
Modified creatinine index is associated with mortality in humans (incident peritoneal dialysis patients) (P = .013).
“For incident PD patients, MCrI quartile was significantly associated with the risk of death from all cause in 12 months (Gray's test, P = .013)”
Humansincident peritoneal dialysis patients12 monthsn = 605
Modified creatinine index as a marker of skeletal muscle mass in peritoneal dialysis patients
Clinical kidney journal
Modified creatinine index predicts mortality in humans (patients undergoing hemodialysis) (adjusted HR 2.51 (95% CI, 1.16-5.41; p = 0.019)).
“compared with those in the high mCI group, subjects in the low mCI group had a higher risk of death for all causes (adjusted HR, 2.51; 95% CI, 1.16-5.41; p = 0.019)”
Humanspatients undergoing hemodialysisn = 218
Renal failure
Skeletal muscle mass
upin humans2
2 studies
Skeletal muscle mass
upin humans2
Modified creatinine index is associated with skeletal muscle mass in peritoneal dialysis patients (r = .684, P < .0001).
“The MCrI during PD significantly correlated with the muscle mass by creatinine kinetics (r = .684, P < .0001)”
Humansin peritoneal dialysis patientsn = 138
Modified creatinine index as a marker of skeletal muscle mass in peritoneal dialysis patients
Clinical kidney journal
Modified creatinine index is associated with skeletal muscle mass in humans (hemodialysis patients; cross-sectional study).
“In the cross-sectional study, modified creatinine index was significantly correlated with skeletal muscle mass measured by BIA.”
Humanshemodialysis patients; cross-sectional studyskeletal musclen = 78
American journal of kidney diseases : the official journal of the National Kidney Foundation
Functional dependence
downin humans1
1 study
Functional dependence
downin humans1
Modified creatinine index predicts functional dependence in humans (maintenance hemodialysis) (AUC 0.682).
“superior predictive capability over the individual indices (GNRI alone AUC = 0.657, mCI alone AUC = 0.682)”
Humansmaintenance hemodialysisn = 208
BMC nephrology
Sarcopenia
upin humans1
1 study
Sarcopenia
upin humans1
Modified creatinine index predicts sarcopenia in humans (patients undergoing hemodialysis) (AUC 0.804 (95% CI, 0.744-0.863; p < 0.001)).
“The area under the curve (AUC) of the mCI to predict probable sarcopenia was 0.804 (95% CI, 0.744-0.863; p < 0.001) for men”
Humanspatients undergoing hemodialysismalesn = 346
Renal failure
All-cause death
upin humans1HR 3
1 study
All-cause death
upin humans1HR 3
Modified creatinine index is linked with a higher risk of all-cause death in humans (per 1 standard deviation decrease) (HR 3.00, 95% CI 2.19–4.09).
“lower mCI (hazard ratio 3.00; 95% confidence interval 2.19, 4.09) and lower GNRI (hazard ratio 1.76; 95% confidence interval 1.45, 2.13) per 1 standard deviation decrease were associated with a higher risk of all-cause death”
Humansper 1 standard deviation decrease3.6-year follow-upn = 472
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation
Bone fracture
downin humans1HR 7.81
1 study
Bone fracture
downin humans1HR 7.81
Modified creatinine index is associated with bone fracture in humans (Q1 versus Q4: adjusted HR 7.81 (95% CI 2.63–23.26); P for trend < 0.001).
“Lower modified creatinine index was associated with increased risk for bone fracture in male and female hemodialysis patients.”
Humansmaintenance hemodialysis; lowest versus highest sex-specific modified creatinine index quartilemedian follow-up 3.9 yearsmales
American journal of kidney diseases : the official journal of the National Kidney Foundation