mtDNA gene expression
1 paper2 findings
- In silico1
Upstream
1mtDNA heteroplasmy and mtRNA modifications
mediatesin humans1
1 study
mtDNA heteroplasmy and mtRNA modifications
mediatesin humans1
mtDNA heteroplasmy and mtRNA modifications mediate mtDNA gene expression in humans (9 instances).
“we find 9 instances where these variations mediate donor age effects on mtDNA gene expression.”
Humansmediation of donor age effects
bioRxiv (Cold Spring Harbor Laboratory)16 Dec 2024Preprint
Associations
1mtDNA heteroplasmy and mtRNA modifications
mixedin humans1
1 study
mtDNA heteroplasmy and mtRNA modifications
mixedin humans1
mtDNA heteroplasmy and mtRNA modifications are associated with mtDNA gene expression in humans (784 associations).
“We identify 109 associations between them and donor age, and 784 associations with tissue-specific mtDNA gene expression.”
Humans49 tissues
bioRxiv (Cold Spring Harbor Laboratory)16 Dec 2024Preprint
Latest
eLife
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
Preprint: experiments in animalsMechanisms
eLife
Tissue-specific responses to TFAM and mtDNA copy number manipulation in prematurely ageing mice
Preprint: experiments in animalsMechanisms
bioRxiv
Tissue-specific apparent mtDNA heteroplasmy and its relationship with ageing and mtDNA gene expression
Preprint: computational studyMechanisms