Methylation variability

Papers on methylation variability

21 papers1 new in 30 days

Friday, October 2

bioRxivOct 2

DNA methylation variability provides a distinct epigenetic marker of human aging heterogeneity

Combining methylation variance with mean methylation levels improved predictions of all-cause mortality across two independent human cohorts.Combining methylation variance with mean methylation levels improved predictions of all-cause mortality across two independent human cohorts.

Differential methylation analysis results.

Preprint: cohort study of 1,445 peopleBiomarkers

Friday, September 18

The Journals of Gerontology, Series ASep 18

DNA methylation variability provides a complementary epigenetic signature of aging heterogeneity: Findings from the Canadian Longitudinal Study on Aging and the Baltimore Longitudinal Study of Aging

Cohort study of 1,445 peopleBiomarkers

Thursday, August 20

bioRxivAug 20

Physics-Informed Modeling of Biological Aging through DNA Methylation Entropy

Preprint: computational studyBiomarkers

Saturday, June 27

Nature AgingJun 27

Human tissues share some age-linked patterns in DNA tags

A computational meta-analysis of more than 15,000 human methylation profiles across 17 tissues found both common and tissue-specific associations with age.A computational meta-analysis of more than 15,000 human methylation profiles across 17 tissues found both common and tissue-specific associations with age.

Meta-analysisMechanisms

Friday, April 10

Clinical EpigeneticsApr 10

Unraveling the complexity of skin's biological aging utilizing epigenetic clocks

Cohort study of 851 peopleBiomarkers

Wednesday, April 1

Clinical and Translational DiscoveryApr 1

Aplastic anaemia: From genetic susceptibility to epigenetic dysregulation

ReviewMechanisms

Saturday, January 3

Aging CellJan 3

Longitudinal Profiling of DNA Methylation Reveals Age-Varying CpG Sites and Novel Insights Into Aging Heterogeneity

Cohort study of 135 peopleDNA methylation

Monday, August 11

GeroScienceAug 11

Analysis of variability and epigenetic age prediction across microarray and methylation sequencing technologies

Study of 100 peopleBiomarkers

Saturday, August 2

Genome ResearchAug 2

Epigenetic drift score captures directional methylation variability and links aging to transcriptional, metabolic, and genetic alterations

Cohort study of 3,538 peopleEpigenetic regulation of gene expression

Monday, November 25

EpigenomesNov 25

Age-Dependent DNA Methylation Variability on the X-Chromosome in Male and Female Twins

Cohort study in peopleDNA methylation

Sunday, February 12

Human GenomicsFeb 12

Data-driven identification and classification of nonlinear aging patterns reveals the landscape of associations between DNA methylation and aging

Computational studyDNA methylation

Wednesday, April 27

Environmental and Molecular MutagenesisApr 27

In vitro relationships of galactic cosmic radiation and epigenetic clocks in human bronchial epithelial cells

Computational studyEpigenetic clock

Monday, November 1

The Journals of Gerontology, Series ANov 1

Impact of Large Granular Lymphocyte Leukemia on Blood DNA Methylation and Epigenetic Clock Modeling in Fischer 344 Rats

Experiments in 61 ratsEpigenetic clock

Wednesday, September 29

GenesSep 29

Years of Schooling Could Reduce Epigenetic Aging: A Study of a Mexican Cohort

Cohort study in peoplePopulations

Wednesday, August 25

Aging CellAug 25

Age patterns of intra-pair DNA methylation discordance in twins: Sex difference in epigenomic instability and implication on survival

Cohort study of 492 peopleBiomarkers

Friday, April 30

Scientific ReportsApr 30

Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear

Computational studyDNA methylation

Saturday, December 5

AgingDec 5

Age-related DNA methylation changes are sex-specific: a comprehensive assessment

Study in peopleDNA methylation

Thursday, November 26

Public Health GenomicsNov 26

Association between SIRT6 Methylation and Human Longevity in a Chinese Population

Case-control study of 129 peopleDNA methylation

Saturday, September 29

EpigeneticsSep 29

Epigenetic influences on aging: a longitudinal genome-wide methylation study in old Swedish twins

Cohort study of 385 peopleDNA methylation

Thursday, September 27

EpigeneticsSep 27

Implementing a method for studying longitudinal DNA methylation variability in association with age

Cohort study of 1,011 peopleDNA methylation

Thursday, March 24

Aging CellMar 24

Reduced DNA methylation patterning and transcriptional connectivity define human skin aging

Cross-sectional study of 108 peopleDNA methylation