Metabolomic signature of malnutrition

Biomarker

1 paper2 findings

  • Humans1

Effects

1

Photoreceptor layer thickness

downin humans1

1 study
  1. Metabolomic signature of malnutrition decreases photoreceptor layer thickness in humans.

    “thinner photoreceptor layer (β = -.214, 95% CI, -0.314 to -0.114, p < .001)”

    Humans

    Malnutrition and age-related macular degeneration: mechanistic insights from UK Biobank metabolomic and imaging data

    The journals of gerontology. Series A, Biological sciences and medical sciences5 Nov 2025

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Associations

1

Age-related macular degeneration

upin humans1HR 1.073

1 study
  1. Metabolomic signature of malnutrition raises the risk of age-related macular degeneration in humans (HR 1.073 per SD increase (95% CI 1.037-1.110)).

    “The metabolomic signature of malnutrition, derived from 127 metabolites, was significantly associated with AMD risk (per SD increase: HR: 1.073, 95% CI, 1.037-1.110, p < .001)”

    Humansn = 444,681

    Malnutrition and age-related macular degeneration: mechanistic insights from UK Biobank metabolomic and imaging data

    The journals of gerontology. Series A, Biological sciences and medical sciences5 Nov 2025

More on Age-related macular degeneration

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