There are 6 papers on Memorial Sloan Kettering-Frailty Index in aging research: 6 observational studies in people.
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“MSK FI (HR 2.4, 95% CI 1.5-4.1, p < 0.001), but not SLNB omission, was an independent predictor of poorer OS.”
- Humans6
Associations
6Mortality
downin humans1upin humans1OR 1.37
2 studies
Mortality
downin humans1upin humans1OR 1.37
Memorial Sloan Kettering-Frailty Index predicts mortality in humans (ovarian cancer surgery) (statistically significantly longer OS for MSK-FI < 3).
“we have observed statistically significantly longer OS when the frailty status index as measured by the MSK-FI was less than 3”
Humansovarian cancer surgeryfemalesn = 114
Surgery in ovarian cancer patients older than 70 years of age and frailty assessment
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Memorial Sloan Kettering-Frailty Index is associated with mortality in humans (cancer and COVID-19) (OR 1.37, 95% CI 1.00, 1.87, p = 0.051).
“increased frailty based on MSK-FI was associated with increased risk of 30-day mortality (OR 1.37, 95% CI 1.00, 1.87; p-value = 0.051)”
Humanscancer and COVID-1930-dayn = 70
Journal of geriatric oncology
Complete surgical resection
downin humans1
1 study
Complete surgical resection
downin humans1
Memorial Sloan Kettering-Frailty Index predicts complete surgical resection in humans (ovarian cancer surgery) (statistically significant lower rates of complete resections).
“the patients from the high-risk group (MSK-FI ≥ 3) had statistically significant lower rates of complete resections”
Humansovarian cancer surgeryfemalesn = 114
Surgery in ovarian cancer patients older than 70 years of age and frailty assessment
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Postoperative mortality
no changein humans1OR 1.02
1 study
Postoperative mortality
no changein humans1OR 1.02
Memorial Sloan Kettering-Frailty Index is associated with postoperative mortality in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.02 (95% CI 0.51-2.00), p = 0.9).
“In univariable analysis, the MSK-FI was associated with postoperative complications [OR 1.57 (95% CI 1.04-2.37), p = 0.03] and ICU admission [OR 2.05 (95% CI 1.30-3.23), p = 0.002], but not with readmission rate [OR 1.29 (95% CI 0.65-2.59), p = 0.5], postoperative mortality [OR 1.02 (95% CI 0.51-2.00), p = 0.9], and hospital stay [β 0.60 (95% CI - 1.19-2.41)].”
Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79
Indian journal of surgical oncology
ICU admission
upin humans1OR 1.97
1 study
ICU admission
upin humans1OR 1.97
Memorial Sloan Kettering-Frailty Index is associated with ICU admission in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.97 (95% CI 1.23-3.16), p = 0.004).
“In multivariable analysis, the frailty index was independently associated with postoperative complications [OR 1.54 (95% CI 1.02-2.34), p = 0.04] and ICU admissions [OR 1.97 (95% CI 1.23-3.16), p = 0.004].”
Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79
Indian journal of surgical oncology
Postoperative complications
upin humans1OR 1.54
1 study
Postoperative complications
upin humans1OR 1.54
Memorial Sloan Kettering-Frailty Index is associated with postoperative complications in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.54 (95% CI 1.02-2.34), p = 0.04).
“In multivariable analysis, the frailty index was independently associated with postoperative complications [OR 1.54 (95% CI 1.02-2.34), p = 0.04]”
Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79
Indian journal of surgical oncology
Overall survival
downin humans1HR 2.4
1 study
Overall survival
downin humans1HR 2.4
Memorial Sloan Kettering-Frailty Index predicts overall survival in humans (multivariable model in thick melanoma) (HR 2.4, 95% CI 1.5-4.1, p < 0.001).
“MSK FI (HR 2.4, 95% CI 1.5-4.1, p < 0.001), but not SLNB omission, was an independent predictor of poorer OS.”
Humansmultivariable model in thick melanoma
Annals of surgical oncology