Memorial Sloan Kettering-Frailty Index

There are 6 papers on Memorial Sloan Kettering-Frailty Index in aging research: 6 observational studies in people.

Biomarker

6 papers study it1 more mentions it7 findings

1 new paper in 30 daysSee all 7 papers on Memorial Sloan Kettering-Frailty Index

“MSK FI (HR 2.4, 95% CI 1.5-4.1, p < 0.001), but not SLNB omission, was an independent predictor of poorer OS.”
Assessment of Frailty Can Guide Decision Making for Utilization of Sentinel Lymph Node Biopsy in Patients with Thick MelanomaAnnals of surgical oncology2021doi:10.1245/s10434-021-10212-w
  • Humans6

Associations

6

Mortality

downin humans1upin humans1OR 1.37

2 studies
  1. Memorial Sloan Kettering-Frailty Index predicts mortality in humans (ovarian cancer surgery) (statistically significantly longer OS for MSK-FI < 3).

    “we have observed statistically significantly longer OS when the frailty status index as measured by the MSK-FI was less than 3”

    Humansovarian cancer surgeryfemalesn = 114

    Surgery in ovarian cancer patients older than 70 years of age and frailty assessment

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

  2. Memorial Sloan Kettering-Frailty Index is associated with mortality in humans (cancer and COVID-19) (OR 1.37, 95% CI 1.00, 1.87, p = 0.051).

    “increased frailty based on MSK-FI was associated with increased risk of 30-day mortality (OR 1.37, 95% CI 1.00, 1.87; p-value = 0.051)”

    Humanscancer and COVID-1930-dayn = 70

    The association between Memorial Sloan Kettering Frailty Index with 30-day survival among patients aged ≥ 75 with cancer and COVID-19

    Journal of geriatric oncology

Complete surgical resection

downin humans1

1 study
  1. Memorial Sloan Kettering-Frailty Index predicts complete surgical resection in humans (ovarian cancer surgery) (statistically significant lower rates of complete resections).

    “the patients from the high-risk group (MSK-FI ≥ 3) had statistically significant lower rates of complete resections”

    Humansovarian cancer surgeryfemalesn = 114

    Surgery in ovarian cancer patients older than 70 years of age and frailty assessment

    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Postoperative mortality

no changein humans1OR 1.02

1 study
  1. Memorial Sloan Kettering-Frailty Index is associated with postoperative mortality in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.02 (95% CI 0.51-2.00), p = 0.9).

    “In univariable analysis, the MSK-FI was associated with postoperative complications [OR 1.57 (95% CI 1.04-2.37), p = 0.03] and ICU admission [OR 2.05 (95% CI 1.30-3.23), p = 0.002], but not with readmission rate [OR 1.29 (95% CI 0.65-2.59), p = 0.5], postoperative mortality [OR 1.02 (95% CI 0.51-2.00), p = 0.9], and hospital stay [β 0.60 (95% CI - 1.19-2.41)].”

    Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79

    The Frailty Based on the Memorial Sloan Kettering Frailty Index for Prediction of Surgical Outcome in Advance Epithelial Ovarian Cancer-Experience of a Single Center in Mexico

    Indian journal of surgical oncology

ICU admission

upin humans1OR 1.97

1 study
  1. Memorial Sloan Kettering-Frailty Index is associated with ICU admission in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.97 (95% CI 1.23-3.16), p = 0.004).

    “In multivariable analysis, the frailty index was independently associated with postoperative complications [OR 1.54 (95% CI 1.02-2.34), p = 0.04] and ICU admissions [OR 1.97 (95% CI 1.23-3.16), p = 0.004].”

    Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79

    The Frailty Based on the Memorial Sloan Kettering Frailty Index for Prediction of Surgical Outcome in Advance Epithelial Ovarian Cancer-Experience of a Single Center in Mexico

    Indian journal of surgical oncology

Postoperative complications

upin humans1OR 1.54

1 study
  1. Memorial Sloan Kettering-Frailty Index is associated with postoperative complications in humans (advanced epithelial ovarian cancer undergoing debulking surgery) (OR 1.54 (95% CI 1.02-2.34), p = 0.04).

    “In multivariable analysis, the frailty index was independently associated with postoperative complications [OR 1.54 (95% CI 1.02-2.34), p = 0.04]”

    Humansadvanced epithelial ovarian cancer undergoing debulking surgeryfemalesn = 79

    The Frailty Based on the Memorial Sloan Kettering Frailty Index for Prediction of Surgical Outcome in Advance Epithelial Ovarian Cancer-Experience of a Single Center in Mexico

    Indian journal of surgical oncology

Overall survival

downin humans1HR 2.4

1 study
  1. Memorial Sloan Kettering-Frailty Index predicts overall survival in humans (multivariable model in thick melanoma) (HR 2.4, 95% CI 1.5-4.1, p < 0.001).

    “MSK FI (HR 2.4, 95% CI 1.5-4.1, p < 0.001), but not SLNB omission, was an independent predictor of poorer OS.”

    Humansmultivariable model in thick melanoma

    Assessment of Frailty Can Guide Decision Making for Utilization of Sentinel Lymph Node Biopsy in Patients with Thick Melanoma

    Annals of surgical oncology

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