Mean semantic noise

Biomarker

2 papers4 findings

  • Human trial2

Interventions

1

Conversational interaction

downin humans2

2 studies
  1. Conversational interaction decreases mean semantic noise in humans (baseline 2.09 ± 0.34 to M6 1.81 ± 0.47, p = 0.009).

    “In the MCI group, baseline MSN was significantly higher than M6 MSN (paired t-test: p = 0.009)”

    Human trialin participants with mild cognitive impairment6 months

    Changes in Conversational Pattern as a Clinical Trial Outcome Using the I-CONECT Data

    GSA 2025 abstract31 Dec 2025

  2. Conversational interaction decreases mean semantic noise in humans (baseline: 2.09 ± 0.34 vs M6: 1.81 ± 0.47, p = 0.009).

    “In the MCI group, baseline MSN was significantly higher than M6 MSN ( p = 0.009)”

    Human trialin MCI group6 months

    Changes in conversational pattern as a clinical trial outcome using the I‐CONECT data

    AAIC 2025 abstract25 Dec 2025

More on Conversational interaction

Associations

1

Mild cognitive impairment

upin humans2

2 studies
  1. Mild cognitive impairment is associated with mean semantic noise in humans (MCI: 2.09 ± 0.34 vs NC: 1.87 ± 0.35, p = 0.024).

    “the MCI group’s MSN was significantly higher than the NC group’s (MCI: 2.09 ± 0.34, NC: 1.87 ± 0.35; p = 0.024) at baseline”

    Human trialat baseline

    Changes in Conversational Pattern as a Clinical Trial Outcome Using the I-CONECT Data

    GSA 2025 abstract31 Dec 2025

  2. Mild cognitive impairment is associated with mean semantic noise in humans (MCI: 2.09 ± 0.34 vs NC: 1.87 ± 0.35, p = 0.024).

    “At baseline, the MCI group's MSN was significantly higher than the NC group's (MCI: 2.09 ± 0.34, NC: 1.87 ± 0.35; p = 0.024).”

    Human trialat baseline

    Changes in conversational pattern as a clinical trial outcome using the I‐CONECT data

    AAIC 2025 abstract25 Dec 2025

More on Mild cognitive impairment

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